The Presymptomatic Era: Operationalizing Early Detection for Type 1 Diabetes
For most of the last century, Type 1 Diabetes announced itself with an acute crisis. A child gets sick, sometimes critically sick, and the diagnosis arrives in the emergency department. The standard clinical response is therefore reactive: wait for symptoms to appear, manage the acute crisis – often Diabetic Ketoacidosis (DKA) – and then initiate…